Author/Authors :
Welsh، نويسنده , , R.C. and Chupp، نويسنده , , T.E. and Coulter، نويسنده , , K.P. and Rosen، نويسنده , , M.S. and Swanson، نويسنده , , S.D. and Agranoff، نويسنده , , B.W.، نويسنده ,
Abstract :
To investigate the feasibility of magnetic resonance imaging with laser-polarized 129Xe we have undertaken the study of time dependences of the 129Xe magnetization in the whole body and its build-up in the brain. We conclude that by increasing the production and absolute polarization of the 129Xe, it will be possible to apply this technique to human brain activation studies based on quantitative measurement of regional cerebral blood flow.
Keywords :
MRI , Xenon , Brain imaging , Laser polarization , rCBF , functional imaging , Hyperpolarization , cerebral blood flow