Author/Authors :
Ovsianko، نويسنده , , S.L. and Chernyavsky، نويسنده , , E.A. and Minchenya، نويسنده , , V.T. and Adzerikho، نويسنده , , I.E. and Shkumatov، نويسنده , , V.M.، نويسنده ,
Abstract :
The effect of ultrasound (US) (26.4 kHz, 26 W/cm2) on the activation process of a mixture of chymotrypsinogen and trypsinogen was studied. US led to a significant decrease in proteolytic activity, as well as inhibition of the activation process in general. It was shown that inhibition of proteinase activity under US influence was a consequence of inhibition of chymotrypsinogen–chymotrypsin transformation and the complete proteolytic trypsin degradation in the proenzymes mixture.
Keywords :
Low-frequency ultrasound , Proenzymes , Activation of serine proteases , HPLC
