Title of article
Efficient synthesis of 2,3-disubstituted-2,3-dihydroquinazolin-4(1H)-ones catalyzed by dodecylbenzenesulfonic acid in aqueous media under ultrasound irradiation
Author/Authors
Chen، نويسنده , , Baohua and Li، نويسنده , , Ji-Tai and Chen، نويسنده , , Guo-Feng، نويسنده ,
Pages
7
From page
59
To page
65
Abstract
Synthesis of 2,3-disubstituted-2,3-dihydroquinazolin-4(1H)-one derivatives catalyzed by dodecylbenzenesulfonic acid was carried out in 80–92% yields at 40–42 °C within 1–2 h in aqueous media via one-pot three-component condensation of isatoic anhydride, aromatic aldehyde and amine under ultrasound irradiation. Convenient work-up procedures, mild reaction conditions, avoiding the use of organic solvents, and friendly to environment are the salient features of this protocol.
Keywords
2 , 3-Dihydroquinazolin-4(1H)-one , Catalysis , Condensation , aqueous media , one-pot synthesis , Ultrasound irradiation
Journal title
Astroparticle Physics
Record number
2008324
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