Analysis of trace elements in scalp hair of healthy people, hyperplasia and breast cancer patients with XRF method

The possibilities of using the energy dispersion X-ray fluorescence analysis (XRF) and synchrotron radiation X-ray fluorescence analysis (SRXFA) for the control of trace elements (TE) content in the hair of women with mammary hyperplasia and cancer are demonstrated. Ten hair samples were taken from 25- to 60-year-old women who have been operated for mammary cancer and from 23 patients under oncologistʹs observation on the occasion of hyperplastic process in the mammary gland (fibrocystous mastopathy). The results of the analyses of trace elements content in the hair of 52 practically healthy women were used as control. sults demonstrated that scalp hair of patients with oncological mammary pathology are characterized by the significant decrease of the concentration of selenium (Se) and zinc (Zn), and by the increase of chromium (Cr). The Se deficit was more pronounced in patients with cancer than in those with hyperplasia (fiducial probability p<0.05)