Author/Authors :
-، - نويسنده Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Mohammadzadeh, A , -، - نويسنده Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Farhat, AS , -، - نويسنده Department of pediatrics, school of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Abdollahi, A , -، - نويسنده Neonatal Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Dastgerdy, E , -، - نويسنده Department of pediatrics, school of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran Bonyadi, B
Abstract :
Resistance to thyroid hormone is an uncommon condition. We report the clinical and laboratory findings of a case with both resistance to thyroid hormone and, a reduced capacity to produce and respond to thyroid hormone. RTH is a disorder characterized by elevated circulating thyroid hormones, state of non-suppressed pituitary TSH secretion and refractoriness to hormone action in peripheral tissues. Resistance to thyroid hormone might be an important additional diagnosis to consider in cases where thyrotropin remains persistently elevated. In this article we described an infant with RTH; her situation was diagnosed incidentally at birth with impaired hypothyroidism screening tests.
