Title of article :
Multivariate analysis of the scattering profiles of healthy and pathological human breast tissues
Author/Authors :
Conceiçمo، نويسنده , , A.L.C. and Antoniassi، نويسنده , , M. and Cunha، نويسنده , , D.M. and Ribeiro-Silva، نويسنده , , A. and Poletti، نويسنده , , M.E.، نويسنده ,
Pages :
4
From page :
870
To page :
873
Abstract :
Scattering profiles of 106 healthy and pathological human breast samples were obtained using the angular dispersive X-ray scattering technique (AD-XRD) and synchrotron radiation covering the momentum transfer interval of 0.7 nm−1≤q(=4π sin(θ/2)/λ)≤70.5 nm−1. Multivariate analysis in the form of discriminant analysis was applied over the whole scattering profile curve of each sample in order to build a model for breast tissue classification. The classification results were validated and compared with histological sample classification obtained by microscopy analysis. Finally, the model allows classifying correctly 91.5% of the samples and presented values of 98.5%, 89.7% and 0.90 for sensitivity, specificity and Cohen’s κ, respectively, in correctly differentiating between healthy and pathological tissues.
Keywords :
X-ray diffraction , Breast tissues , Multivariate analysis
Journal title :
Astroparticle Physics
Record number :
2017837
Link To Document :
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