Author/Authors :
Giokaris، نويسنده , , N.D. and Loudos، نويسنده , , G.K. and Maintas، نويسنده , , D. and Papapanagiotou، نويسنده , , D. and Nikita، نويسنده , , K.S. and Uzunoglu، نويسنده , , N.K. and Karabarbounis، نويسنده , , A. and Papanicolas، نويسنده , , C.N. and Stiliaris، نويسنده , , E. and Archimandritis، نويسنده , , S.C. and Varvarigou، نويسنده , , A.D. and Stefanis، نويسنده , , C.N. and Majewski، نويسنده , , S. and ، نويسنده ,
Abstract :
The results of studies conducted with a small field of view gamma camera based on a Position Sensitive Photomultiplier Tube (PSPMT) and a pixelized scintillator crystal, made of CsI(Tl), are reported. Using a computer-controlled step motor allowing object rotation, projection data from several angles are acquired. Images of slices of the object are obtained and compared with the use of a Filtered Backprojection and a Maximum Likelihood algorithm. Phantom studies have shown a spatial resolution of 2–3 mm in both two and three dimensions, and mice experiments have shown successful SPECT imaging of small organs. 3D images obtained from a paraffin cylinder phantom and from a 99mTc water solution phantom showed that a “hot” spot with a size down to 0.2 ml can be detected with a resolution of about 2 mm if the tumor to background activity ratio is 6:1.
Keywords :
Maximum likelihood , “Hot” spot , PSPMT , Breast phantoms , high resolution , Sensitivity
