Detector technology challenges for nuclear medicine and PET

The challenges facing the development of new detector technology for single photon imaging and positron emission tomography (PET) are considered. There is currently great interest in functional imaging with radionuclides, particularly PET, triggered by new clinical applications and developments in molecular and cell biology. Multi-modality systems that combine radionuclide imaging with CT present new challenges, as do very high resolution systems for imaging small animals. Whilst for PET there are some fairly well defined routes to improving performance, the basic design of single photon systems has remained unchanged for many years. This review outlines the challenges that must be addressed by detector physicists in order to obtain significant advances in performance, and indicates some of the approaches currently being adopted. Emphasis is given to PET which is where the greatest opportunities appear to lie.