Author/Authors :
Wolber، نويسنده , , J. J. Ellner، نويسنده , , F. and Fridlund، نويسنده , , B. and Gram، نويسنده , , A. and Jَhannesson، نويسنده , , H. and Hansson، نويسنده , , Paul G. and Hansson، نويسنده , , L.H. and Lerche، نويسنده , , M.H. and Mهnsson، نويسنده , , S. and Servin، نويسنده , , R. and Thaning، نويسنده , , M. and Golman، نويسنده , , K. and Ardenkjوr-Larsen، نويسنده , , J.H.، نويسنده ,
Abstract :
A method to generate strongly polarized nuclear spins in solution has been developed, using Dynamic Nuclear Polarization (DNP) at a temperature of 1.2 K, and at a field of 3.354 T, corresponding to an electron spin resonance frequency of 94 GHz. Trityl radicals are used to directly polarize 13C and other low-γ nuclei. Subsequent to the DNP process, the solid sample is dissolved rapidly with a warm solvent to create a solution of molecules with highly polarized nuclear spins. Two main applications are proposed: high-resolution liquid state NMR with enhanced sensitivity, and the use of the hyperpolarized solution as an MR imaging agent.
Keywords :
Hyper polarization , Dynamic nuclear polarization , NMR spectroscopy , Magnetic Resonance Imaging
