Author/Authors :
Siu، نويسنده , , K.K.W. and Butler، نويسنده , , S.M. and Beveridge، نويسنده , , T. and Gillam، نويسنده , , J.E. and Hall، نويسنده , , C.J. and Kaye، نويسنده , , A.H. and Lewis، نويسنده , , R.A. and Mannan، نويسنده , , K. and McLoughlin، نويسنده , , G. and Pearson، نويسنده , , S. D. Round، نويسنده , , A.R. and Schültke، نويسنده , , E. and Webb، نويسنده , , G.I. and Wilkinson، نويسنده , , S.J.، نويسنده ,
Abstract :
Conventional neuropathological analysis for brain malignancies is heavily reliant on the observation of morphological abnormalities, observed in thin, stained sections of tissue. Small Angle X-ray Scattering (SAXS) data provide an alternative means of distinguishing pathology by examining the ultra-structural (nanometer length scales) characteristics of tissue. To evaluate the diagnostic potential of SAXS for brain tumors, data was collected from normal, malignant and benign tissues of the human brain at station 2.1 of the Daresbury Laboratory Synchrotron Radiation Source and subjected to data mining and multivariate statistical analysis. The results suggest SAXS data may be an effective classifier of malignancy.
Keywords :
Brain tumors , DATA MINING , Synchrotron radiation , small angle X-ray scattering
