Author/Authors :
Grignon، نويسنده , , C. and Barbet، نويسنده , , J. and Bardiès، نويسنده , , M. and Carlier، نويسنده , , T. and Chatal، نويسنده , , J.F. and Couturier، نويسنده , , O. and Cussonneau، نويسنده , , J.P. and Faivre، نويسنده , , A. and Ferrer، نويسنده , , L. and Girault، نويسنده , , S. and Haruyama، نويسنده , , T. and Le Ray، نويسنده , , P. and Luquin، نويسنده , , L. and Lupone، نويسنده , , S. and Métivier، نويسنده , , V. and Morteau، نويسنده , , E. and Servagent، نويسنده , , N. and Thers، نويسنده , , D.، نويسنده ,
Abstract :
We report on a new nuclear medical imaging technique based on the measurement of the emitter location in the three dimensions with a few mm spatial resolution using β+γ emitters. Such measurement could be realized thanks to a new kind of radio-nuclides which emit a γ-ray quasi-simultaneously with the β+ decay. The most interesting radio-nuclide candidate, namely 44Sc, will be potentially produced at the Nantes cyclotron ARRONAX. The principle is to reconstruct the intersection of the classical line of response (obtained with a standard PET camera) with the direction cone defined by the third γ-ray. The emission angle measurement of this additional γ-ray involves the use of a Compton telescope for which a new generation of camera based on a liquid xenon (LXe) time projection chamber is considered. GEANT3 simulations of a large acceptance LXe Compton telescope combined with a commercial micro-PET (LSO crystals) have been performed and the obtained results will be presented. They demonstrate that a good image can be obtained from the accumulation of each three-dimensional measured position. A spatial resolution of 2.3 mm has been reached with an injected activity of 0.5 MBq for a 44Sc point source emitter.
