Author/Authors :
Gonias، نويسنده , , P. and Bertsekas، نويسنده , , N. and Karakatsanis، نويسنده , , N. and Saatsakis، نويسنده , , G. and Gaitanis، نويسنده , , A. and Nikolopoulos، نويسنده , , D. and Loudos، نويسنده , , G. and Papaspyrou، نويسنده , , L. and Sakellios، نويسنده , , N. and Tsantilas، نويسنده , , X. and Daskalakis، نويسنده , , A. and Liaparinos، نويسنده , , P. and Nikita، نويسنده , , K. and Louizi، نويسنده , , A. and Cavouras، نويسنده , , D. and Kandarakis، نويسنده , , I. and Panayiotakis، نويسنده , , G.S.، نويسنده ,
Abstract :
The recently developed Geant4 Application for Tomographic Emission (GATE) toolkit is a Monte Carlo simulation platform developed for PET and SPECT simulations and is freely distributed by the OpenGATE collaboration. GATE provides the ability of modelling time-dependent phenomena, such as geometry element movements and source decay kinetics, allowing the simulation of time curves under realistic acquisition conditions. The purpose of this paper was to validate a GATE model for the simulation of the Siemens PET Biograph™ 6 scanner. This three-dimensional GATE model simulated 24336 LSO (Lutetium Oxyorthosilicate) detectors grouped into 144 blocks in accordance with the vendorʹs specifications. GATE results were compared with experimental data, obtained in accordance with the NEMA NU 2-2001 performance measurement protocol. The scatter phantom used by this protocol was also modelled within GATE, allowing us to simulate scatter fraction and count rate performance measurements.
Keywords :
Gate , PET , Monte Carlo simulations , Validation , Biograph 6 , NEMA NU 2-2001