Title of article
Fragmentation analysis by superconducting ion detectors in matrix-assisted laser desorption/ionization (MALDI)
Author/Authors
Ohkubo، نويسنده , , M. and Shigeri، نويسنده , , Y. and Kinumi، نويسنده , , T. and Saito، نويسنده , , N. and Ukibe، نويسنده , , M. and Chen، نويسنده , , Y.E. and Kushino، نويسنده , , A. and Kurokawa، نويسنده , , A. and Sato، نويسنده , , H. and Ichimura، نويسنده , , S.، نويسنده ,
Pages
3
From page
779
To page
781
Abstract
Fragmentation of precursor ions of peptides or proteins is very promising for sequencing with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (TOF-MS). Neutral fragments as well as ions produced by post-source decay (PSD) were measured by a superconducting tunnel junction detector in a linear TOF-MS. It has been demonstrated that the PSD fragments are observable as event bands with different kinetic energies at the same TOF as that of the precursor ions of polystyrene with a nominal mass of 200 kDa and bovine serum albumin of 66.43 kDa.
Keywords
Mass Spectroscopy , Post-source decay , Superconducting tunnel junction
Journal title
Astroparticle Physics
Record number
2028415
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