Author/Authors :
Maghsoodlou، Malek Taher نويسنده , , Masoumnia، Amin نويسنده Department of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, Iran. , , Mousavi، Mir Rasul نويسنده Department of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, Iran. , , Hazeri، Nourollah نويسنده Department of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, Iran. , , Aboonajmi، Jasem نويسنده Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, P. O. Box 98135-674, Zahedan, Iran , , Habibi-Khorasani، Sayyed Mostafa نويسنده Department of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, Iran. , , Kiaee، Shiva نويسنده Department of Chemistry, The University of Sistan and Baluchestan, P.O. Box 98135-674, Zahedan, Iran. ,
Abstract :
Na2SO4 as an inexpensive and effective catalyst has provided a green protocol for the synthesis of tetrahydrobenzo[b]pyran, pyrano[2,3-d]pyrimidinone and dihydropyrano[3,2c]chromene derivatives from the three-component domino reaction of aromatic aldehydes and malononitrile with 4-hydroxycoumarin/ dimedone/ barbituric acid in ethanol/water as a mixture of solvent that, this mixture entirely is green solvent. Products could simply be separated from the catalyst. Using neutral and mild conditions, short reaction time, environmentally benign procedure, high to excellent yields of the products and easy work-up without using column chromatography are the advantages of this method.
