Snakehead (Channa striata) Extracts Treatment towards Hyperglycemic Mice (Mus musculus) Blood Glucose Levelsand Pancreatic Histology Structure

Hyperglycemic condition induced by islets of Langerhans (island of Langerhans) tissue damage of the pancreas. Albumin treatment was expected to generate islets of Langerhans tissue. Snakehead (Channa striata) extracts contained roughly a million albumin so that, it was inquired to generate its pancreatic tissue of mice (Mus musculus) hyperglycemic. Alloxan at 190 mg/kg of weight doses with intraperitoneal (IP) injection used to encourage mice hyperglycemic. Various doses during 14 days were carried out under it treatment. Blood glucose levels had measured by Accu-Check Roche® glucose meter (glucometer). Histological preparation for mice pancreas obtained through Haematoxylin and Eosin (H&E) Staining for paraffin sections, where it observed under Olympus® BX-41microscope image. As much of 0.14846 mL/day had generated 68.78% islets ofLangerhans tissue of the pancreas and reduced 34.42% blood glucose levels as long 14 days were obtained as the result of snakehead albumin treatment.