Title of article
FIV induced encephalopathy: early brain lesions in the absence of viral replication in monocyte/macrophages. A pathogenetic model
Author/Authors
Silvotti، نويسنده , , Lucia and Corradi، نويسنده , , Attilio and Brandi، نويسنده , , Giorgio and Cabassi، نويسنده , , Aderville and Bendinelli، نويسنده , , Mauro and Magnan، نويسنده , , Mauro and Piedimonte، نويسنده , , Giuseppe، نويسنده ,
Pages
9
From page
263
To page
271
Abstract
FIV induced encephalopathy represents a model for the study of the neuropathogenesis of AIDS. It has yet to be determined whether massive viral replication is a prerequisite for the development of early brain lesions. Using a drug delivery system developed by us, we have shown that early encephalic lesions appear in FIV infected subjects even when viral transport within the brain has been markedly reduced or blocked.
Keywords
FIV , Pathenogenetic model , Brain lesions , Encephalopathy
Journal title
Astroparticle Physics
Record number
2053806
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