Author/Authors :
صادقي ، رامين نويسنده , , جليل زاده شيرواني، سيده زهرا نويسنده , , حسن زاده ، مليحه نويسنده , , يوسفي ، زهره نويسنده yousefi, zohreh , كدخدايان، سيما نويسنده , , شريفي ، نوريه نويسنده sharifi, nourieh , صدري، كيوان نويسنده Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Sadri, Kayvan , زكوي، سيد رسول نويسنده Nuclear Medicine Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran. Zakavi, Seyed Rasoul
Abstract :
Vulvar cancer is a rare gynecological malignancy with mainly lymphatic spread. Sentinel node mapping plays an important
role in the management of this gynecological malignancy. In the current study, we reported our experience in sentinel node
mapping of vulvar cancer and review the literature accordingly. Since the introduction of sentinel node mapping to the
surgical oncology community of our university in 2004, we had two operable vulvar cancer patients who were candidate for
sentinel node mapping for inguinal lymph node staging. In the current study, we reported these two cases in details and a
brief review of literature on sentinel node mapping in vulvar cancer was done. We specifically discussed the overall
accuracy, importance of blue dye injection, learning curve effect, frozen section, excisional biopsy and location of the
tumors. Overall sentinel node mapping is a safe and effective method for inguinal lymph node staging in vulvar cancers. In
order to perform sentinel node mapping efficiently, paying attention to the details is of utmost importance.