Title of article :
Semi-quantitative segmental perfusion scoring in myocardial perfusion
Author/Authors :
دباغ كاخكي، وحيدرضا نويسنده بخش پزشكي هسته اي، بيمارستان امام رضا(ع)، دانشگاه علوم پزشكي مشهد , , صادقي ، رامين نويسنده , , ترابيان-كاخكي، مريم نويسنده 3Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran Torabian-Kakhki, Maryam , پزشكي راد، مسعود نويسنده Pezeshki rad , Masoud , صدري، كيوان نويسنده Department of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Sadri, Kayvan
Issue Information :
فصلنامه با شماره پیاپی 42 سال 2014
Abstract :
Introduction: It is recommended that the physician apply at least a semi-quantitative segmental scoring system in
myocardial perfusion SPECT. We aimed to assess the agreement between automated semi-quantitative analysis using QPS
(quantitative Perfusion SPECT) software and visual approach for calculation of summed stress score (SSS), summed rest
score (SRS) and summed difference score (SDS).
Methods: We retrospectively studied 1782 consecutive patients who had undergone two-day stress-rest Tc99m-MIBI
myocardial perfusion SPECT. Based on 17-segment 5-scale scoring system, SSS, SRS and SDS were calculated visually and
using QPS software.
Results: There was good correlation between visual analysis and QPS software in calculation of SSS and SRS and a fair
correlation for SDS. However, there was statistically significant difference between two methods. By Bland-Altman analyses
mean value of the differences (estimated bias) differs significantly from 0 on the basis of 1-sample t-test. Based on bias,
Precision and 95% limits of agreement, discrepancies between measurements indicate no agreement equally through the
range of measurements, so there is a proportional bias. Based on SSS, SRS and SDS ?3 and SSS, SRS and SDS > 3, there
was fair concordance between the visual assessment and automated QPS calculation. Kappa statistics was 0.41 (P < 0.001),
0.69 (P < 0.001) and 0.25 (P < 0.001) for SSS, SRS and SDS respectively.
Conclusion: Although semi-quantification sores by visual and automated analysis is correlated, the agreement assessed by
Bland-Altman analysis is not high especially in more extensive perfusion defects. Semi-quantitative automated analysis
should be used as a supplement to the visual assessment.
Journal title :
Iranian Journal of Nuclear Medicine
Journal title :
Iranian Journal of Nuclear Medicine