Author/Authors :
Bardeau، نويسنده , , Ch.E. and Eberhardt، نويسنده , , A.S. and Nyquist، نويسنده , , R.M. and Parikh، نويسنده , , A.N. and Shreve، نويسنده , , A.P. and Swanson، نويسنده , , B.L.، نويسنده ,
Abstract :
Shifts in the main phase transition temperatures caused by a highly specific, protein-receptor interaction in a hybrid bilayer architecture are probed utilizing temperature programmed infrared vibrational spectroscopy. The specific case of cholera toxin attachment to glycolipid receptors embedded in a phospholipid outer layer at a hydrophobized silicon surface is investigated. Potential applications of the approach as a signal amplification method in biosensors will be discussed.
Keywords :
Micelles and solution self-assembly , optical absorption , atomic force microscopy , infrared spectroscopy
