Title of article
Multifunctional nanocarriers and intracellular drug delivery
Author/Authors
Sawant، نويسنده , , Rupa R. and Torchilin، نويسنده , , Vladimir P.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
7
From page
269
To page
275
Abstract
Multifunctional nanocarriers for the delivery and targeting of therapeutic and diagnostic agents in cancer therapy have received significantly increased interest in recent years.
l multifunctional nanocarriers engineered from a wide range of materials with consolidation of various functionalities for long circulation, targetability, stimuli-sensitivity, intracellular delivery for therapy and imaging have been shown to be capable of killing the desired target diseased cells with minimal side effects to provide enhanced contrast during imaging for disease location and monitor both the fate of the nanocarrier and treatment in real time. This review highlights recent advances in the design and engineering of multifunctional nanocarriers, along with the importance of intracellular delivery.
Keywords
Intracellular delivery , Cell-penetrating peptide , Ligand-targeted , Long-circulating , Multimodal imaging , Theranostics , Stimuli-sensitive , Nanocarriers
Journal title
Current Opinion in Solid State and Materials Science
Serial Year
2012
Journal title
Current Opinion in Solid State and Materials Science
Record number
2089327
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