• Title of article

    Multifunctional nanocarriers and intracellular drug delivery

  • Author/Authors

    Sawant، نويسنده , , Rupa R. and Torchilin، نويسنده , , Vladimir P.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2012
  • Pages
    7
  • From page
    269
  • To page
    275
  • Abstract
    Multifunctional nanocarriers for the delivery and targeting of therapeutic and diagnostic agents in cancer therapy have received significantly increased interest in recent years. l multifunctional nanocarriers engineered from a wide range of materials with consolidation of various functionalities for long circulation, targetability, stimuli-sensitivity, intracellular delivery for therapy and imaging have been shown to be capable of killing the desired target diseased cells with minimal side effects to provide enhanced contrast during imaging for disease location and monitor both the fate of the nanocarrier and treatment in real time. This review highlights recent advances in the design and engineering of multifunctional nanocarriers, along with the importance of intracellular delivery.
  • Keywords
    Intracellular delivery , Cell-penetrating peptide , Ligand-targeted , Long-circulating , Multimodal imaging , Theranostics , Stimuli-sensitive , Nanocarriers
  • Journal title
    Current Opinion in Solid State and Materials Science
  • Serial Year
    2012
  • Journal title
    Current Opinion in Solid State and Materials Science
  • Record number

    2089327