Bioactivity of CaO–MgO–SiO2 glass ceramics synthesized using transferred arc plasma (TAP) process

Glass ceramic with a nominal composition of 35.6% CaO, 12.8% MgO and 51.6% SiO2 was prepared by transferred arc plasma processing. The in vitro bioactivity of the plasma synthesized CaO–MgO–SiO2 glass ceramic was examined for its biomedical applicability which was evaluated by immersion in simulated body fluid at 36.5 °C for several days. The apatite particles were found to be formed on the surface of the glass ceramic and grew with the passage of soaking time. The simulated body fluid test results showed the formation of carbonated hydroxyapatite like layer on the surface of the glass ceramic. The cytocompatibility was evaluated through human fibroblast proliferation. The fibroblasts adhere, spread, and proliferate on the CaO–MgO–SiO2 glass ceramic, and the cell proliferation was more obvious.