Synthesis and characterization of magnetic bioactive glass-ceramics containing Mg ferrite for hyperthermia

Novel magnetic bioactive glass-ceramics (M GC) were synthesized by doping Mg ferrite to wollastonite–fluorapatite-containing glass-ceramics. The phase composition was investigated by XRD. The magnetic property was measured by VSM. The in vitro bioactivity was investigated by simulated body fluid (SBF) soaking experiment. Cell growth on the surface of the material was evaluated by co-culturing osteoblast-like ROS17/2.8 cells with M GC. The results showed that CaSiO3, Ca2MgSi2O7, Ca5(PO4)3F and Fe2MgO4 were the main phases of M GC. Under a magnetic field of 10,000 Oe, the saturation magnetization and coercive force of M GC were 7.2 emu/g and 175 Oe, respectively. After soaking in SBF for 14 days, a lot of hydroxyapatite containing CO32− was observed on the surface of M GC. The experiment of co-culturing cells with M GC showed that osteoblast-like ROS17/2.8 cells could attach well on the surface of M GC. The material has the potential to be used as thermoseeds for hyperthermia.