Macroporous hybrid frameworks for bone graft substitute

Hybrid nanocomposite of poly(methyl methacrylate) reinforced with hydroxyapatite has been fabricated by phase separation mechanism of the polymer in the presence of a solvent having low solubility. The process demonstrates the formation of a three-dimensional honeycomb like macroporous structure of the hybrid material having struts patterned with micropores. Such mechanically stable open cell foam like structure has a potential to be used as a non-resorbable bone implant.