Author/Authors :
Yang، نويسنده , , Xuemin and Zhao، نويسنده , , Yulin and Chen، نويسنده , , Yunjian and Liao، نويسنده , , Xiali and Gao، نويسنده , , Chuanzhu and Xiao، نويسنده , , Dan and Qin، نويسنده , , Qixue and Yi، نويسنده , , Dong and Yang، نويسنده , , Bo، نويسنده ,
Abstract :
The characterization, inclusion complexation behavior and binding ability of the inclusion complexes of mangiferin (MGF) with β-cyclodextrin and its derivatives (hydroxypropyl-β-cyclodextrin (HPβCD), sulfobutyl ether β-cyclodextrin (SBEβCD) and mono (6-ethylene-diamino-6-deoxy)-β-cyclodextrin (ENβCD)) were investigated in both solution and solid state by means of PL spectroscopy, 1H and 2D NMR, XRD, TG and DSC. The results showed that the water solubility and thermal stability of MGF were significantly increased in the inclusion complex with cyclodextrins. The MGF/CDs complexes will be potentially useful for the design of a novel formulation of mangiferin for herbal medicine.
Keywords :
inclusion complexation , ?-Cyclodextrins , Binding ability , Mangiferin
