Title of article
A new putative G-protein coupled receptor gene associated with the immune system of rainbow trout (Oncorhynchus mykiss)
Author/Authors
Kiryu، نويسنده , , Ikunari and Kِllner، نويسنده , , Bernd and Kuroda، نويسنده , , Akashi and Ototake، نويسنده , , Mitsuru and Dijkstra، نويسنده , , Johannes Martinus، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
11
From page
117
To page
127
Abstract
A putative G-protein coupled receptor (GPCR) gene belonging to the rhodopsin-like family was detected in rainbow trout and designated LPSenhR-1. Only moderate homology (<35%) was present with known GPCRs. Semi-quantitative RT-PCR indicated that the gene was expressed predominantly in lymphoid tissues, with highest expression associated with cells of the monocyte/macrophage lineage. Expression was strongly up-regulated by injection with LPS but not by infection with infectious haematopoietic necrosis virus.
Keywords
Macrophage , Infectious haematopoietic necrosis virus , rainbow trout , LPS , G-protein coupled receptor , Monocyte
Journal title
Fish and Shellfish Immunology
Serial Year
2003
Journal title
Fish and Shellfish Immunology
Record number
2106779
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