Author/Authors :
Blanc، نويسنده , , P.J. and Laussac، نويسنده , , J.P. and Le Bars، نويسنده , , J. and Le Bars، نويسنده , , P. and Loret، نويسنده , , M.O. and Pareilleux، نويسنده , , A. and Prome، نويسنده , , D. and Prome، نويسنده , , J.C. and Santerre، نويسنده , , A.L. and Goma، نويسنده , , G.، نويسنده ,
Abstract :
Following our investigations on red pigments and monascidin co-production by Monascus species, the antibiotic called monascidin A was characterized as citrinin. Evidence was given by qualitative methods, mass spectra and NMR. Citrinin, a nephrotoxic agent was produced both by Monascus purpureus and Monascus ruber, either in submerged culture of concentrations of 270 and 340 mg/l, respectively, or in solid state culture of concentration of 100 and 300 mg/kg dried matter, respectively. Since citrinin is a toxic product, it is essential that the production of red pigments as food additives from Monascus spp. avoid the occurrence of citrinin.
