Title of article :
Lack of DNA-damaging activity of five non-nutritive sweeteners in the rat hepatocyte/DNA repair assay
Author/Authors :
Jeffrey ، نويسنده , , A.M. and Williams، نويسنده , , G.M، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Abstract :
The non-nutritive sweeteners acesulfame-K, aspartame, cyclamate, saccharin and sucralose were tested for DNA damaging activity in the rat hepatocyte/DNA repair assay. Using hepatocytes from F344 and Sprague–Dawley male rats, all were inactive despite strong responses for the positive control, 2-aminofluorene.
Keywords :
DNA damage , Genotoxic , Unscheduled DNA synthesis , hepatocytes , Sweeteners
Journal title :
Food and Chemical Toxicology
Journal title :
Food and Chemical Toxicology
