Author/Authors :
Ghanaie، Roxana M. نويسنده Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences , , SHIARI، Reza نويسنده MD,Ph.D,Assistant Professor of Pediatric Rheumatology,Shahid Beheshti University of Medical Sciences,Tehran,Iran , , Karimi، Abdollah نويسنده , , Armin، Shahnaz نويسنده , , Fahimzad، Alireza نويسنده , , Shiva، Faride نويسنده Pediatric Infections Research Center, Shahid Beheshti University of Medical Sciences , , Arzanian، Mohammad Taghi نويسنده Department of Pediatrics, Division of Pediatric Oncology, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences ,
Abstract :
Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and potentially life-threatening disease and has to be considered in the differential diagnosis of many conditions. HLH comprises two different conditions that are difficult to differentiate; Familial hemophagocytic lymphohistiocytosis (FHLH) or familial erythrophagocytic lymphohistiocytosis (FEL), and Secondary hemophagocytic syndromes (secondary HLH, sHLH). Herein, we report a case series of Iranian children with HLH and describe the symptoms and outcome of this disease in Iran.
