Author/Authors :
Belicchi، نويسنده , , M. and Cancedda، نويسنده , , R. and Cedola، نويسنده , , A. and Fiori، نويسنده , , F. and Gavina، نويسنده , , M. Vittoria Giuliani، نويسنده , , A. and Komlev، نويسنده , , V.S. and Lagomarsino، نويسنده , , S. and Mastrogiacomo، نويسنده , , M. and Renghini، نويسنده , , C. and Rustichelli، نويسنده , , F. and Sykovà، نويسنده , , E. and Torrente، نويسنده , , Y.، نويسنده ,
Abstract :
Stem cell based tissue engineering therapies involve the administration of ex vivo manipulated stem cell populations with the purpose of repairing and regenerating damaged or diseased tissue. Currently available methods of monitoring transplanted cells are quite limited. To monitor the outcomes of stem cell therapy longitudinally requires the development of non-destructive strategies that are capable of identifying the location, magnitude, and duration of cellular survival and fate. The recent development of imaging techniques offers great potential to address these critical issues by non-invasively tracking the fate of the transplanted cells. This review offers a focused presentation of some examples of the use of imaging techniques connected to the nanotechnological world in research areas related to stem cells. In particular investigations will be considered concerning tissue-engineered bone, treatment of intervertebral disc degeneration, treatment by human stem cells of muscular dystrophy of Duchenne in small animal models and the repair of spinal cord injuries.
Keywords :
Imaging techniques , Stem cells , Nanoparticles , Tissue engineering
