Title of article
Trimethyl Phosphite Mediated Simple Synthesis of Coumarins and Azacoumarins Through the Reaction of Phenols or Hydroxypyridines and Dimethyl Acetylenedicarboxylate (DMAD) or Diethyl Acetylenedicarboxylate (DEAD)
Author/Authors
-، - نويسنده Faculty of Chemistry, Islamic Azad University, Tehran North Branch, Tehran, I.R. IRAN Moradi, Shahram , -، - نويسنده Department of Chemistry, Islamic Azad University, Arak Branch, Arak, I.R. IRAN Azarakhshi, Fatemeh , -، - نويسنده Faculty of Chemistry, Islamic Azad University, Tehran North Branch, Tehran, I.R. IRAN Masoumi Shahi, Akbar
Issue Information
فصلنامه با شماره پیاپی 0 سال 2008
Pages
5
From page
35
To page
39
Abstract
-
Abstract
Protonation of the reactive intermediate produced in the reaction between trimethyl phosphite and dimethyl acetylenedicarboxylate or diethyl acetylenedicarboxylate by resorcinol, 5-methylresorcinol, 2,5-dihydroxyacetophenone, 4-chloro-2-methylphenol, 4-chloro-3,5-dimethy-lphenol, 4-hydroxypyridine, 2-hydroxypyridine, 3-hydroxypyridine, or 8-hydroxyquinoline leads to vinylphosphonium salts, which undergo Michael addition with the conjugate base of the OH-acid to produce highly functionalized 2-oxo-2H-chromene or azacoumarins in good yields.
Journal title
Iranian Journal of Chemistry and Chemical Engineering (IJCCE)
Serial Year
2008
Journal title
Iranian Journal of Chemistry and Chemical Engineering (IJCCE)
Record number
2151920
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