Author/Authors :
Potter، نويسنده , , C.S. and Chu، نويسنده , , H and Frey، نويسنده , , B and Green، نويسنده , , Charles W. Kisseberth، نويسنده , , N and Madden، نويسنده , , T.J and Miller، نويسنده , , K.L and Nahrstedt، نويسنده , , K and Pulokas، نويسنده , , Amy R. Reilein، نويسنده , , A and Tcheng، نويسنده , , D and Weber، نويسنده , , D and Carragher، نويسنده , , B، نويسنده ,
Abstract :
We have developed a system to automatically acquire large numbers of acceptable quality images from specimens of negatively stained catalase, a biological protein which forms crystals. In this paper we will describe the details of the system architecture and analyze the performance of the system as compared to a human operator. The ultimate goal of the system if to automate the process of acquiring cryo-electron micrographs.
Keywords :
three-dimensional electron microscopy , Automated data acquisition , Microscopic methods , Instrument control
