Author/Authors :
Padalkar، نويسنده , , Sonal and Zhao، نويسنده , , Jianxiu and Stuart، نويسنده , , Kate and Panitch، نويسنده , , Alyssa and Rickus، نويسنده , , Jenna and Stanciu، نويسنده , , Lia، نويسنده ,
Abstract :
We report a new sample preparation method that allows the direct transmission electron microscopy evaluation of the architectural characteristics of biomolecules entrapped in gel matrices. We demonstrate that this sample preparation technique can be used for the identification and ultrastructural characterization of liposomes, collagen I and collagen III embedded in gel matrices, and has the potential to be useful for transmission electron microscopy (TEM) characterization of other biomolecule–gel matrix systems.
