Author/Authors :
Sarabandi، Afsaneh نويسنده Department of Nursing, Faculty of Medical Sciences, Islamic Azad University, Zahedan Branch, Zahedan, Iran. , , Manafi Shabestari، Rima نويسنده Department of Hematology and Blood Transfusion, Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. , , Farshi، Yadolah نويسنده Department of Hematology and Blood Transfusion, Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. , , Tabibian، Shadi نويسنده Department of Hematology, Tehran University of Medical Sciences, Tehran, Iran Tabibian, Shadi , Dorgalaleh، Akbar نويسنده Department of Hematology,Tehran University of Medical Sciences , Tehran, Iran Dorgalaleh, Akbar , Esmaeili Reykande، Samira نويسنده Department of Hematology and Blood Transfusion, Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. , , Kia، Seyyed Hossein نويسنده Tehran Heart Centre, Tehran University of Medical Sciences, Tehran, Iran. , , Varmaghani، Bija نويسنده Department of Hematology and Blood Transfusion, Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. , , Rashidpanah، Jamal نويسنده Tehran Heart Centre, Tehran University of Medical Sciences, Tehran, Iran. ,
Abstract :
A B S T R A C T
Background and Aims: It is believed that uremia causes destruction of white blood cells (WBC) leading to leukopenia. This study attempted to assess the exact effect of uremia on WBC count.
Materials and Methods: This case-control study was conducted on 120 uremic patients and 100 non-uremic control subjects. All cases were examined for determination of urea and creatinine in their serum; complete blood counts were also determined.
Results and Conclusion: In healthy male individuals, the mean values of serum urea and creatinine were 14.5±1.9 and 0.9±0.2 mg/dL, respectively. In females the serum urea concentration was the same as males, but mean serum creatinine was 0.66±3.2 mg/dL. In the patients group, the mean concentration of serum urea for both sexes was 83±2.4 mg/dL. The mean values of creatinine in male and female patients were 2.4±1.3 mg/dL and 2.1±1.7 mg/dL, respectively. The mean total leukocyte counts in case and control groups were 6.08± 2.24 and 6.17± 2.43 ×109/L, respectively (p=0.71). Our results indicate that uremia cannot change leukocyte count.
