Title of article
Effect of Uremia on White Blood Cell Count in Patients with Renal Failure
Author/Authors
Sarabandi، Afsaneh نويسنده Department of Nursing, Faculty of Medical Sciences, Islamic Azad University, Zahedan Branch, Zahedan, Iran. , , Manafi Shabestari، Rima نويسنده Department of Hematology and Blood Transfusion, Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. , , Farshi، Yadolah نويسنده Department of Hematology and Blood Transfusion, Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. , , Tabibian، Shadi نويسنده Department of Hematology, Tehran University of Medical Sciences, Tehran, Iran Tabibian, Shadi , Dorgalaleh، Akbar نويسنده Department of Hematology,Tehran University of Medical Sciences , Tehran, Iran Dorgalaleh, Akbar , Esmaeili Reykande، Samira نويسنده Department of Hematology and Blood Transfusion, Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. , , Kia، Seyyed Hossein نويسنده Tehran Heart Centre, Tehran University of Medical Sciences, Tehran, Iran. , , Varmaghani، Bija نويسنده Department of Hematology and Blood Transfusion, Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. , , Rashidpanah، Jamal نويسنده Tehran Heart Centre, Tehran University of Medical Sciences, Tehran, Iran. ,
Issue Information
فصلنامه با شماره پیاپی 0 سال 2015
Pages
4
From page
21
To page
24
Abstract
چكيده
مقدمه: بنظر مي رسد كه اورمي باعث تخريب گلبول هاي سفيد خون شده و لكوپني را موجب مي گردد. از اينرو اين مطالعه با هدف تاثير اورمي بر تعداد گلبول هاي سفيد خون طراحي شد.
مواد و روش ها: اين مطالعه مورد-شاهدي بر روي 120 بيمار مبتلا به اورمي و 100 فرد بعنوان گروه كنترل انجام شد. ميزان اوره و كراتينين سرم و تعداد سلولهاي خون در تمام نمونه هاي مورد مطالعه تعيين گرديد.
نتايج و نتيجه گيري: در گروه شاهد، ميانگين ميزان اوره سرم 9/1±5/14 ميلي گرم در دسي ليتر و ميانگين مقدار كراتينين 2/0±9/0در مردان و 2/3±66/0 ميلي گرم در دسي ليتر در زنان بود. در گروه بيماران، ميانگين مقادير اوره 4/2±83 ميلي گرم در دسي ليتر و ميانگين كراتينين درمردان و زنان به ترتيب 3/1±4/2 و 7/1±1/2 ميلي گرم در دسي ليتر بود. ميانگين تعداد گلبولهاي سفيد در گروه مورد 2/2±08/6 و در گروه شاهد 43/2±17/6 با واحد 109در ليتر بود(71/0=p (. نتايج ما نشان داد كه اورمي نمي تواند باعث تغيير در تعداد گلبولهاي سفيد شود.
Abstract
A B S T R A C T
Background and Aims: It is believed that uremia causes destruction of white blood cells (WBC) leading to leukopenia. This study attempted to assess the exact effect of uremia on WBC count.
Materials and Methods: This case-control study was conducted on 120 uremic patients and 100 non-uremic control subjects. All cases were examined for determination of urea and creatinine in their serum; complete blood counts were also determined.
Results and Conclusion: In healthy male individuals, the mean values of serum urea and creatinine were 14.5±1.9 and 0.9±0.2 mg/dL, respectively. In females the serum urea concentration was the same as males, but mean serum creatinine was 0.66±3.2 mg/dL. In the patients group, the mean concentration of serum urea for both sexes was 83±2.4 mg/dL. The mean values of creatinine in male and female patients were 2.4±1.3 mg/dL and 2.1±1.7 mg/dL, respectively. The mean total leukocyte counts in case and control groups were 6.08± 2.24 and 6.17± 2.43 ×109/L, respectively (p=0.71). Our results indicate that uremia cannot change leukocyte count.
Journal title
International Journal of Medical Laboratory
Serial Year
2015
Journal title
International Journal of Medical Laboratory
Record number
2168246
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