Author/Authors :
Ando، نويسنده , , M. and Hashimoto، نويسنده , , E. and Hashizume، نويسنده , , H. and Hyodo، نويسنده , , K. and Inoue، نويسنده , , H. and Kunisada، نويسنده , , T. and Maksimenko، نويسنده , , A. and Mori، نويسنده , , K. and Rubenstein، نويسنده , , E. and Roberson، نويسنده , , J. and Shimao، نويسنده , , D. and Sugiyama، نويسنده , , H. and Takeda، نويسنده , , K. and Toyofuku، نويسنده , , F. and Ueno، نويسنده , , E. and Umetani، نويسنده , , K. and ، نويسنده ,
Abstract :
This paper reports, the application of synchrotron radiation to basic medicine at SPring-8 involving instrumentation and medical application of imaging and scattering. Emphasis should be laid on X-ray dark-field imaging (DFI) whose goal is clinical diagnosis of organs that have been invisible by ordinary techniques. Development of this technique is under way both at SPring-8 and KEK. The X-ray optics of DFI comprises a Bragg asymmetric monochro-collimator and a Laue case analyzer with a diffraction index of 4 4 0 using the X-ray energy of 35 keV ( λ = 0.0354 nm ) in a parallel position. This analyzer that can provide with 80 mm×80 mm view size has 2.15 mm thickness. At present the spatial resolution is around 5–10 μm. Visibility of some organs such as soft bone tissue at excised human femoral head and breast cancer tissue is under test. This preliminary test shows that the DFI seems feasible in clinical diagnosis. Furthermore, a perspective view of application of synchrotron radiation to clinical medicine in Japan will be given.
Keywords :
Laue diffraction filter , Pseudoclinical diagnosis , Excised human femoral head , Refraction , articular , KEK , SPring-8 , Photon factory , Clinical application , X-ray dark-field imaging , Monochro-collimator , Synchrotron radiation
