Title of article
Wolfram syndrome: A case report
Author/Authors
Eskandarifar، Alireza نويسنده Urology & Nephrology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran , , Sedaghat، Banafsheh نويسنده Resident, Department of Pediatrics Diseases, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran , , Janany، Somayeh نويسنده Resident, Department of Pediatrics Diseases, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran , , Hosseiny، Mozhgan نويسنده Faculty of Management and Medical Informatics, Tabriz University of Medical Science, Tabriz, Iran , , Gharib، Alireza نويسنده Deputy of Research and Technology, Kurdistan University of Medical Sciences, Sanandaj, Iran ,
Issue Information
فصلنامه با شماره پیاپی 4 سال 2014
Pages
3
From page
95
To page
97
Abstract
Wolfram syndrome (WFS) is a rare disease inherited as an autosomal dominant trait. Type I diabetes mellitus and optic atrophy are the main symptoms of the disease. It is also known as DIDMOAD syndrome due to the association of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. WFS may be associated with other disorders such as kidney failure, gonadal atrophy, and mental and behavioral disorders. This report is about a 14-year-old teenager who had suffered from vision loss and cataracts when he was 4 years old. At the age of 7 he has been diagnosed with type I diabetes mellitus due to polyuria and polydipsia. At the age of 12 he developed diabetes insipidus, neural hearing loss, urinary incontinence and bilateral hydronephrosis, neurogenic bladder, and increased blood pressure. Physicians should think of this disease and recommend genetic counselling before marriage.
Journal title
Chronic Diseases Journal
Serial Year
2014
Journal title
Chronic Diseases Journal
Record number
2208824
Link To Document