Title of article
Study on ibuprofen/montmorillonite intercalation composites as drug release system
Author/Authors
Zheng، نويسنده , , J.P. and Luan، نويسنده , , L. and Wang، نويسنده , , H.Y. and Xi، نويسنده , , L.F. and Yao، نويسنده , , K.D.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
297
To page
301
Abstract
The present paper focused on the intercalation of ibuprofen (IBU) into montmorillonite as a sustained release drug carrier. The intercalation compounds were characterized by X-ray diffraction (XRD), Fourier transformed infrared (FT-IR), and thermogravimetric analysis (TGA). The basal spacing of montmorillonite increased from 1.25 nm to 1.57 nm. The decomposition temperature of intercalated IBU was increased to 471 °C. The in vitro release experiments revealed that IBU was released from MMT steadily and pH dependent.
Keywords
IBUPROFEN , In vitro release , Montmorillonite , intercalation
Journal title
Applied Clay Science:an International Journal on the Application...
Serial Year
2007
Journal title
Applied Clay Science:an International Journal on the Application...
Record number
2221806
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