Author/Authors :
Shiryazdi، Seyyed Mostafa نويسنده Department of Surgery, Shahid Sadoughi University of Medical Sciences, Yazd, Iran , , Kargar، Saeed نويسنده , , Dehghan، Mohammad Ali نويسنده 2Shahid Sadoughi University of Medical Sciences, Yazd, IR Iran Dehghan, Mohammad Ali , Neamatzadeh، Hosein نويسنده 3Breast Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, IR Iran Neamatzadeh, Hosein
Abstract :
Background: The various studies related to different aspects of breast cancer has or is being carried out all over the world, but the breast cancer developing risk factors in patients and high-risk people have not been well understood yet. The ABO/Rh systems blood group role as a factor increasing risk to getting some pathology has proven. So the survey of probable association between ABO/Rh systems blood group and breast cancer can be useful.
Patients and Methods: This cross-sectional study included 197 women with breast cancer who referred to either Yazd Shahid Sadoughi hospital or Dr. Mortaz hospital during six years (2007 - 2013) because of diagnosis or treatment. The patient’s demographic and clinical data were extracted and evaluated from their clinical documents.
Results: During 6 years, 375 reports of breast cancer were registered in 2 hospitals totally, that only data of 197 reports can be surveyed. The mean and limit of patient’s age were 44 ± 5.3 years and 17 - 70 years respectively. Most patients (93.4%) have Rh+ blood group system. Blood type A+ was the most prevalent among patients. Then O+ and B+ was the most which their frequency distribution was 21.4% (42) and 9.1% (18) respectively. The least frequency distribution of this blood group system was related to AB+ which is observed in only 4% (8) of patients.
Conclusions: Blood type A+ has the most association with breast cancer according to the findings this article and can be used as a paraclinical marker in treatment and consulting of patients and high-risk people.