Title of article
NaHSO4-SiO2: An Efficient Reusable Green Catalyst for Selective C-3 Propargylation of Indoles with Tertiary Propargylic Alcohols
Author/Authors
-، - نويسنده Department of Chemistry, University of the Free State, P.O. Box 339, Bloemfontein 9300, SOUTH AFRICA Gohani, Mukut , -، - نويسنده Department of Chemistry, University of the Free State, P.O. Box 339, Bloemfontein 9300, SOUTH AFRICA H. van Tonder, Johannes , -، - نويسنده Department of Chemistry, University of the Free State, P.O. Box 339, Bloemfontein 9300, SOUTH AFRICA C.B. Benzuidenhoudt, Barend
Issue Information
فصلنامه با شماره پیاپی 0 سال 2015
Pages
7
From page
11
To page
17
Abstract
-
Abstract
Although several methods for the preparation of 4o propargyl indole derivatives have been published, this synthetic transformation is complicated by the tendency of 3o propargyl alcohols to form allenium intermediates in acidic media. It is therefore a challenge to find an efficient method for the C-3 propargylation of indoles with 3° propargylic alcohols. In this paper we wish to report on the successful application of silica gel impregnated with NaHSO4 as catalyst for the preparation of 4o propargyl indole derivatives.
Journal title
Iranian Journal of Chemistry and Chemical Engineering (IJCCE)
Serial Year
2015
Journal title
Iranian Journal of Chemistry and Chemical Engineering (IJCCE)
Record number
2279250
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