Author/Authors :
KHOSRAVI، ALIREZA نويسنده , , Pourheidar، Behrouz نويسنده Resident, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Science, Isfahan, Iran , , Roohafza، Hamidreza نويسنده Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Moezzi، Masoumeh نويسنده Assistant Professor, Department of Community Medicine, Shahrekord University of Medical Science, Shahrekord, Iran , , Mousavi، Mehdi نويسنده Resident, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Science, Isfahan, Iran , , Hajiannejad، Alireza نويسنده Resident, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Science, Isfahan, Iran , , Bidram، Peyman نويسنده Resident, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Science, Isfahan, Iran , , Gharipour، Mojgan نويسنده Hypertension Research Center, Isfahan Cardiovascular Research Institute, IUMS, Isfahan , , Shirani، Shahin نويسنده Associate Professor, Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Golshahi، Jafar نويسنده Associate Professor, Isfahan Cardiovascular , , Boshtam، Mansoureh نويسنده Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Sarrafzadegan، Nizal نويسنده MD, Professor of Cardiology, Isfahan Cardiovascular Research Center, IUMS, Isfahan ,
Abstract :
BACKGROUND: Hypertension (HTN) considers as one of the most common risk factors, which
potentially raises the risk of cardiovascular disease. Regarding high prevalence of HTN among
Iranian population this study designed to examine a range of socio-demographic and clinical
variables to determine the association with failure to achieve blood pressure control in a cohort
of hypertensive subjects.
METHODS: This retrospective cohort study is a part of Isfahan cohort study which carried out on
adults aged 35 years old or more. Subjects with confirmed HTN entered in this sub-study. For
all subjects questionnaire included socio-demographic characteristics, clinical data and lifestyle
behavior completed by trained nurses. Uncontrolled HTN was defined as systolic and diastolic
blood pressure more than 140/90 in the presence or absent of pharmacological treatment.
RESULTS: The prevalence of uncontrolled men was significantly higher than controlled in both
2001 and 2007 (P < 0.001). A significant association was found between sex and control of
blood pressure: compared with women, being men [odds ratio (OR) = 2.31; 95 % confidence
interval (CI) = 1.64-3.24] was significantly associated with uncontrolled HTN in 2001 and
(OR = 2.38; 95% CI = 1.78-3.18). Among lifestyle behaviors, tendency for more consumption of
salty foods increased the risk of uncontrolled HTN in 2001 by 1.73 times [OR = 1.73, 95%
CI = 1.20-2.50, (P = 0.003)]. Patients who were naive to mono-therapy without considering the
type of antihypertensive drug were found to be associated with uncontrolled blood pressure
(OR = 0.14; 95 % CI =0.1-0.2).
CONCLUSION: Uncontrolled HTN was sex, marital status, diabetes, tendency to salty foods and
medication adherence. Assessment of them presence of these risk factors is warranted to
recommend an aggressive HTN management with the goal of reducing excessive risk of
cardiovascular events caused by uncontrolled HTN.
