Author/Authors :
Keshvari، Mahtab نويسنده Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran Keshvari, Mahtab , Asgary، Sedigheh نويسنده PhD, Associate Professor of Pharmacognosy, Isfahan Cardiovascular Research Center, Applied Physiology Research Center, IUMS, Isfahan , , Jafarian-dehkordi، Abbas نويسنده Professor, School of Pharmacy and Pharmacutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran , , Najafi، Somayeh نويسنده Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Ghoreyshi-Yazdi، Seyed Mojtaba نويسنده School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran ,
Abstract :
BACKGROUND: Lipid oxidation is the main deterioration process that occurs in vegetable oils.
This process was effectively prevented by natural antioxidants. Cinnamomum zeylanicum
(Cinnamon) is rich with antioxidants. The present study was conducted to evaluate the effect of
cinnamon on malondialdehyde (MDA) rate production in two high consumption oils in Iranian
market.
METHODS: Chemical composition of cinnamon essential oil was analyzed by gas
chromatography-mass spectroscopy (GC-MS). 200 ?l each oil, 50 ?l tween 20, and 2 ml of 40
Mm AAPH solutions were mixed and the prepared solution was divided into four glass vials.
Respectively, 50 ?l of 500, 1000 and 2000 ppm of cinnamon essential oil were added to three
glass vials separately and one of the glass vials was used as the control. All of the glass vials were
incubated at 37° C water bath. Rate of MDA production was measured by thiobarbituric acid
(TBA) test at the baseline and after the 0.5, 1, 2, 3 and 5 hours.
RESULTS: Compounds of cinnamon essential oil by GC-MS analysis such as cinnamaldehyde
(96.8%), alpha-capaene (0.2%), alpha-murolene (0.11%), para-methoxycinnamaldehyde (0.6%)
and delta-cadinen (0.4%) were found to be the major compounds. For both oils, maximum rate
of MDA production was achieved in 5th hours of heating. Every three concentrations of
cinnamon essential oil significantly decreased MDA production (P < 0.05) in comparison with
the control.
CONCLUSION: Essential oil of cinnamon considerably inhibited MDA production in studied oils
and can be used with fresh and heated oils for reduction of lipid peroxidation and adverse free
radicals effects on body.
