Author/Authors :
Rouhi Boroujeni ، Hamid نويسنده Cellular and Molecular Research Center , , Rouhi-Boroujeni، Hojjat نويسنده Member of Student Research Committee, Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran , , Rouhi Boroujeni، Parnia نويسنده Cellular and Molecular Research Center , , Sedehi، Morteza نويسنده Medical Plants Research Center, Shahrekord University of Medical Sciences, Shahrekord, Iran ,
Abstract :
BACKGROUND: The present study aimed to describe the long-term alterations of pulmonary
function and also to describe its association with post-operative pain after coronary artery
bypass grafting (CABG) surgery.
METHODS: In this prospective study, thirty non-smoker male patients undergoing isolated onpump
CABG were consecutively included in this study. Pulmonary function measurements were
performed, in a sitting position, preoperatively, a week postoperatively, and 6 months after the
surgery using a Medical Graphics PF/Dx pulmonary function system. Pain was determined by
using visual analog scale (VAS) pain scores with a standardized questionnaire’s.
RESULTS: Regarding functional class, all patients had New York Heart Association (NYHA)
Class II to III. A week after operation, a severe restrictive pulmonary impairment was revealed
with a mean decrease in VC to 60.9 ± 9.2% and in forced expiratory volume in one second
(FEV1) to 64.6 ± 12.2% of pre-operative values (P < 0.001). Regarding sternotomy related pain,
the mean pain VAS score was preoperatively 3.3 ± 1.5 that reached to 6.2 ± 2.5 and 4.8 ± 2.2 1
week and 6 months after the operation (P < 0.001). The trend of the changes in pain score
within 6 months of operation was significantly similar to the trend of the changes in some
pulmonary function indices such as FEV% and residual volume (RV).
CONCLUSION: A significant reduction is expected in most pulmonary functional parameters
following CABG despite normal pulmonary function state preoperatively. Severe pain originated
from sternotomy may be an important factor related to pulmonary dysfunction following CABG.