Author/Authors :
Mohammadian-Hafshejani، Abdollah نويسنده Deputy of Health, Isfahan University of Medical Sciences, Isfahan AND PhD Candidates, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran , , Sarrafzadegan، Nizal نويسنده MD, Professor of Cardiology, Isfahan Cardiovascular Research Center, IUMS, Isfahan , , Hosseini، Shidokht نويسنده Researcher, Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Baradaran، Hamid Reza نويسنده Assistant Professor, Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Roohafza، Hamidreza نويسنده Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran , , Sadeghi، Masoumeh نويسنده , , Asadi-Lari، Mohsen نويسنده Oncopathology Research Centre, Tehran University of Medical Sciences, Tehran, Iran ,
Abstract :
BACKGROUND: Seasonal variation in admissions and mortality due to acute myocardial
infarction has been observed in different countries. Since there are scarce reports about this
variation in Iran, this study was carried out to determine the existence of seasonal rhythms in
hospital admissions for acute myocardial infarction, and in mortality due to acute myocardial
infarction (AMI) in elderly patients in Isfahan city.
METHODS: This prospective hospital-based study included a total of 3990 consecutive patients
with acute myocardial infarction admitted to 13 hospitals from January 2002 to December
2007. Seasonal variations were analyzed with the Kaplan-Meier table, log rank test, and Cox
regression model.
RESULTS: There was a statistically significant relationship between the occurrence of heart
disease based on season and type of acute myocardial infarction anatomical (P < 0.001). The
relationship between the occurrence of death and season and type of AMI according to
International Classification of Diseases code 10 (ICD) was also observed and it was statistically
significant (P = 0.026). Hazard ratio for death from acute myocardial infarction were 0.96
[Confidence interval of 95% (95% CI) = 0.78-1.18], 0.9 (95%CI = 0.73-1.11), and 1.04 (95%CI =
0.85-1.26) during spring, summer, and winter, respectively.
CONCLUSION: There is seasonal variation in hospital admission and mortality due to AMI;
however, after adjusting in the model only gender and age were significant predictor factors.
