Author/Authors :
Sapmaz، Ismail نويسنده Alanya Research Center Cardiovascular Surgery, Baskent University, Antalya, Turkey , , Saba، Tonguc نويسنده Alanya Research Center Cardiovascular Surgery, Baskent University, Antalya, Turkey , , Haberal، Cevahir نويسنده Alanya Research Center Cardiovascular Surgery, Baskent University, Antalya, Turkey , , Toktamis، Aydin نويسنده Alanya Research Center Family Medicine, Baskent University, Antalya, Turkey , , Cakmak، Melis نويسنده Alanya Research Center Anesthesiology, Baskent University, Antalya, Turkey , , Cicek، Davran نويسنده Department of Cardiology, School of Medicine, Baskent University, Antalya, Turkey ,
Abstract :
Hemorheological factors, such as viscosity, are significant in determining blood flow characteristics and play an important role in the pathogenesis of thrombotic events and, therefore, cerebrovascular diseases. The viscosity of fluids depends on; particle concentration, shape of the particles, pH of the fluid, and temperature. Blood includes many different kinds of proteins such as; fibrinogen, albumin and globulins. Plasma viscosity and hematocrit values are the major determinants of whole blood viscosity (1-3). It should be bought to one’s attention, that although albumin comprises more than half of the total serum proteins (4), its effect on blood viscosity is very low (5). This is an inverse situation according to our physical knowledge of fluid viscosity. An interesting study by Lacombe et al. (6) showed that an elevation in fibrinogen concentration, leads to a more aggregated structure in red blood cell suspensions. Immediately after the albumin was added, increased aggregability of red blood cell was improved It sems that there is a negative correlation between erythrocyte aggregability and plasma albumin.
