Author/Authors :
Sarrafzadegan، Nizal نويسنده MD, Professor of Cardiology, Isfahan Cardiovascular Research Center, IUMS, Isfahan , , Gharipour، Mojgan نويسنده Hypertension Research Center, Isfahan Cardiovascular Research Institute, IUMS, Isfahan , , Sadeghi، Masoumeh نويسنده , , Nouri، Fatemeh نويسنده Department of law, Payame Noor University (PNU), PO Box: 19395-3697, IR. Iran , , Asgary، Sedigheh نويسنده PhD, Associate Professor of Pharmacognosy, Isfahan Cardiovascular Research Center, Applied Physiology Research Center, IUMS, Isfahan , , Zarfeshani، Sonia نويسنده BSc, Isfahan Cardiovascular Research Center, Isfahan University of Medical Sciences, Isfahan, Iran ,
Abstract :
BACKGROUND: The prevalence of metabolic syndrome (MetS) is increasing among children and
adolescents. However, the prevalence of this disorder varies based on its different definitions.
This study aimed to determine the prevalence of MetS in Iranian adolescents in junior high and
high schools according to the definitions provided by the International Diabetes Federation
(IDF) and De Ferranti.
METHODS: Overall, 1039 junior high school and 953 high school students were selected using
multistage random sampling. Demographic data was collected using validated questionnaires.
Fasting blood sugar, total cholesterol, triglyceride, high-density lipoprotein cholesterol (HDL-C)
and low-density lipoprotein cholesterol (LDL-C) levels were determined. Waist circumference
and blood pressure were measured by trained individuals. Subjects with MetS were selected
according to two definitions provided by the IDF and De Ferranti. Chi-square and Fisher’s exact
tests were used to compare the prevalence of MetS and its components based on sex, school
level, and the two definitions.
RESULTS: The mean age of junior high and high school students was 13.11 ± 1.21ad 15.93 ± 1.07
years old, respectively. The prevalence of MetS among all participants was 4.8% and 12.7%
according to the definitions by the IDF and De Ferranti, respectively. It was significantly higher
among boys compared to girls. According to the IDF definition, low HDL-C and hypertension
were the most frequent components. Based on the De Ferranti, abdominal obesity and
hypertriglyceridemia were the most frequent components.
CONCLUSION: The prevalence of MetS was higher in both groups of students based on De
Ferranti definition compared to the IDF definition. The prevalence was not significantly
different in boys and girls. Further studies to investigate the most suitable definition of MetS for
Iranian adolescents are necessary.
