Canine Babesiosis in China Caused by Babesia gibsoni: A Molecular Approach.
Yao، Da-Wei نويسنده College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China. Yao, Da-Wei , Jiang، Jing-Ya نويسنده College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China. Jiang, Jing-Ya , Yu، Ze-Zhong نويسنده YuXi Agriculture Vocation-Technical College, Yuxi, Yunnan, China. Yu, Ze-Zhong , Yao، Dong-Qin نويسنده College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China. Yao, Dong-Qin , Yang، De-Ji نويسنده College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, Jiangsu, China. Yang, De-Ji , Zhao، Yanbing نويسنده ,
Background: To provide a point of reference to study the epidemiology and clin-ical expression of canine babesiosis in China.
Methods: A total of 30 dogs infected with canine babesiosis were evaluated by mean of clinical history, physical examination, hematological, restriction fragment length polymorphism of PCR products (PCR-RFLP) and sequencing analysis.
Result: The most prevalent clinical abnormalities were lethargy (100%), anorexia (100%), pale or icteric mucous membranes (80%), fever (70%) and dark urine (70%). Hematology parameters revealed that anemia and thrombocytopenia were the major abnormalities in blood of dogs infected with canine babesia. The results of PCR-RFLP and sequencing analysis indicated that B. gibsoni was the main species responsible for canine babesiosis cases at the time of the study in Nanjing, China.
Conclusions: The results provide valuable information for better understanding of the epidemiology of canine babesiosis in China.