Author/Authors :
Mohaghegh، Mohammad Ali نويسنده Department of Medical Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IR Iran , , Ghazvini، Kiarash نويسنده , , Jafari ، Rasool نويسنده Department of Parasitology and Mycology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran , , Alikhani، Mohammad Yousef نويسنده Department of Microbiology, Faculty of Medicine, Hamedan University of Medical Sciences, Hamedan, IR Iran , , Safari، Marzieh نويسنده Department of Microbiology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran , , Azari Garamjan، Gholam Ali نويسنده Department of Microbiology and Virology, Mashhad University of Medical Sciences, Mashhad, IR Iran Azari Garamjan, Gholam Ali , Falahi، Jamal نويسنده Department of Microbiology and Virology, Mashhad University of Medical Sciences, Mashhad, IR Iran Falahi, Jamal , Bordbar، Davod نويسنده Department of Microbiology and Virology, Mashhad University of Medical Sciences, Mashhad, IR Iran Bordbar, Davod
Abstract :
Staphylococci bacteria cause different diseases, varies from mild skin infections to serious bacteremia. Also they are a major cause of nosocomial and community-acquired infections globally. Staphylococcus aureus and Staphylococcus epidermidis are the two important opportunistic pathogens of the staphylococci that both can cause bacteremia. The aim of the present study was to investigate the prevalence and antibiotic resistance pattern of S. aureus and S. epidermidis among blood culture of patients of Ghaem Educational, Research and Treatment Center, Mashhad, Iran, during 6 years (2006 - 2011). In this retrospective study, hospital medical records of 28000 patients referred to Ghaem Educational, Research and Treatment Center, Mashhad, Iran, who were suspicious of blood infections during 6 years (2005-2011), were extracted. The patient’s blood culture with staphylococcal growth and their antibiogram results during 2006 - 2011 were collected and studied. Staphylococcus spp. were isolated from 600 (2.14%) out of 28000 blood cultures. Furthermore, 420 (70%), 170 (28.3%) and 10 (1.7%) out of 600 bacterial isolates identified as S. epidermidis, S. aureus and other Staphylococcus spp., respectively. Ampicillin, amoxicillin, cefixime, ceftazidime, penicillin, oxacillin, nalidixic acid and cephepime were the most antibiotics that the isolates were resistant against. Also vancommycin and chloramphenicol were the most effective antibiotics against S. epidermidis and S. aureus, respectively. Prevalence of Staphylococcal bacteremia caused by S. epidermidis is fairly high comparing to S. aureus among patients referred to Ghaem Educational, Research and Treatment Center, Mashhad, Iran. Also the resistance rate of Staphylococcus spp. isolated from blood against commonly used antibiotic is high, but there are some highly sensitive antibiotic against the infection.
