Author/Authors :
Keshtkar Jahromi، Maryam نويسنده 1Infectious Diseases and Tropical Medicine Research Center, Shahid Beheshti University, M.C., Tehran, Iran Keshtkar Jahromi, Maryam , Sharifi- mood، Batool نويسنده ,
Abstract :
Ebola hemorrhagic fever (EHF) is amongst severe and fatal viral hemorrhagic fevers. In February 2014, a strain of the Ebola virus appeared in Guinea and then in Liberia, Sierra Leone, and Mali. The aim of this study was to review the literature on EHF and discuss its routes of transmission and prevention. We searched medical databases (PubMed, Scopus) from July 1970 to July 2014. The key words for the literature search were as follows; Ebola hemorrhagic fever, epidemiology, transmission routes, clinical manifestation, treatment and prophylaxis. On the basis of the literature search, the researchers believe that bats are the most likely reservoir. Four of five subspecies of Ebola virus have caused disease in humans. Manifestation of Ebola begins abruptly with a sudden onset of an influenza-like syndrome characterized by general malaise, fever, sore throat, severe headache, joint pain, muscle pain and chest pain. There is no Ebola virus specific treatment. Treatment is usually supportive and includes minimizing invasive procedures, and balancing fluids and electrolytes. Adequate sterilization procedures isolate patients and this is a major step towards prevention of transmission of virus to other people. Ebola viruses are highly contagious. Understanding the epidemiology, clinical presentation, prompt diagnosis, suitable treatment and isolation are the main factors for prevention of death and transmission of virus to other people