Author/Authors :
Karimi، Abdollah نويسنده , , Rafiei Tabatabaei، Sedigheh نويسنده Pediatric Infections Research Center, Department of Pediatric Infectious Diseases, Shahid Beheshti University of Medical Sciences , , Amanati، Ali نويسنده Hamadan University of Medical sciences, Hamadan, Iran , , Ghoroubi، Javad نويسنده Department of Surgery, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences , , Karami، Mohsen نويسنده Department of Medical Entomology and Vector Control, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. Karami, Mohsen
Abstract :
Bacillus Calmette-Guérin (BCG) vaccine, a live attenuated Mycobacterium bovis strain, is administrated to all newborn infants in endemic regions according to the current World Health Organization (WHO) recommendation. We report a 10-month-boy who was a known case of severe combined immunodeficiency (SCID) admitted with multi-focal fusiform painful swelling in his hands. He had undergone bone marrow transplantation 7 weeks before admission. Multidisciplinary management was done to treat this rare post-transplant occurrence of Bacillus Calmette-Guérin complication. BCG vaccination administrated routinely in Iran, given that of no screening program for primary immune deficiency currently achieved in our country, exact attention to reschedule of immunization programs in suspicious newborn (with primary immune deficiency) always is necessary and is one of the most effective strategy to prevent BCG complication
