Title of article
Hepatoprotective activity of Mammea africana ethanol stem bark extract
Author/Authors
-، - نويسنده Department of Pharmacology and Toxicology Faculty of Pharmacy, University of Uyo, Uyo, Nigeria Okokon, Jude Efiom , -، - نويسنده Department of Pharmacology and Toxicology Faculty of Pharmacy, University of Uyo, Uyo, Nigeria Burata Bawo, Michael , -، - نويسنده Department of Pharmacology and Toxicology Faculty of Pharmacy, University of Uyo, Uyo, Nigeria Orji Mbagwu, Herbert
Issue Information
دوماهنامه با شماره پیاپی 0 سال 2016
Pages
12
From page
248
To page
259
Abstract
-
Abstract
Mammea africana Sabine (Guttiferae) stembark, a common plant, traditionally used to treat various diseases and ailments was evaluated for hepatoprotective potentials against paracetamol- induced liver injury in rats. The hepatoprotective effect of the stembark extract (30-90 mg/kg) was evaluated by the assay of liver function parameters: total and direct bilirubin, serum protein and albumin, total cholesterol, alanine aminotransaminase (ALT), aspartate aminotransaminase (AST), and alkaline phosphatase activities (ALP), antioxidant enzymes: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH) and histopathological study of the liver. The administration of the stembark extract caused significant (p
Journal title
Avicenna Journal of Phytomedicine AJP)
Serial Year
2016
Journal title
Avicenna Journal of Phytomedicine AJP)
Record number
2385348
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