Author/Authors :
Saed، Samaneh نويسنده Antimicrobial Resistance Research Center, Buali Research Institute, Department of Microbiology and Virology, Medical School, Mashhad University of Medical Sciences, Mashhad, IR Iran , , Yazdanpanah، Malektaj نويسنده Ghaem University Hospital, Mashhad University of Medical Sciences, Mashhad, IR Iran , , Lal-Dehghani، Mitra نويسنده Ghaem University Hospital, Mashhad University of Medical Sciences, Mashhad, IR Iran , , Khalighi، Amir Reza نويسنده Mashhad University of Medical Sciences, Mashhad, Iran. , , Honarmand، Mahbubeh نويسنده Ghaem University Hospital, Mashhad University of Medical Sciences, Mashhad, IR Iran , , Afrough، Parviz نويسنده Department of Laboratory Sciences, Golestan Hospital, Ahvaz, Jundishapur Medical Science University, Ahvaz, IR Iran , , Ghazvini، Kiarash نويسنده ,
Abstract :
Background: Acinetobacter spp. emerged as an opportunistic pathogen for hospital-acquired infections. Recently, increasing antibiotic resistance among Acinetobacter spp. has worsened the problem. The aim of this study was to investigate the emerging trend of infection due to Acinetobacter in Ghaem University Hospital, Mashhad during 2006-2012
Methods: The demographic data and information about redisposing factors was collected. Appropriate bacteriological samples were collected and Acinetobacter spp. was isolated. Antibiotics susceptibility pattern of these isolates against different antimicrobials agents was determined.
Results: Results confirmed that Acinetobacter spp. cause 20.9% of nosocomial infection during this period. The trend of Acinetobacter nosocomial infection was increasing and patients with risk factors such as COPD, bronchectasia, diabetes mellitus were more prone to infection. There was significant association between these infections and invasive procedures such as catheterization, mechanical ventilation and broad-spectrum antibiotics usage.
Conclusion: Understanding trends in causative organisms of nosocomial infection can help us to better define our infection control policy